Posted: Jan 13, 2022
APPLY

Transgenic Animal Model Core Research Lab Specialist Intermediate

University of Michigan - Ann Arbor, MI
Full-time
Application Deadline: Jan 26, 2022
Staff Scientist

How to Apply

A cover letter is required for consideration for this position and should be attached as the first page of your resume. The cover letter should address your specific interest in the position and outline skills and experience that directly relate to this position.

Summary

The Biomedical Research Core Facilities (BRCF), as part of the Medical School's Office of Research (OoR), has an opening in the Transgenic Animal Model Core. The BRCF Transgenic Core was established in 1989 to provide access to transgenic animal technology in an efficient & effective manner. Researchers consult with the Core in all phases of genome editing, transgenic and gene targeting research from experimental design to mouse breeding. The Transgenic Core also offers a full suite of cryopreservation and assisted reproduction (IVF) services. The Core's mission is to provide access to complex technology that allows Principal Investigators to focus on their research instead of developing the tools for their research. 

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally.  Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems.  In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

  • Excellent medical, dental and vision coverage effective on your very first day
  • 2:1 Match on retirement savings

Responsibilities*

Micromanipulation workstation operation for the pronuclear microinjection of fertilized mouse eggs. Workstation is comprised of high power research microscope, two micromanipulators, Femtojet picospritzer, piston syringes, video system, and antivibration platform

Culture of living fertilized mouse and rat eggs in cell culture incubators. Superovulation, mating, unmating, mice and rats. Treating mice and rats with injections. Collection of fertilized eggs from mice and rats

Stereomicroscope assisted surgical transfer of mouse eggs to pseudopregnant female mice and rat eggs to pseudopregnant female rats

In vitro fertilization of mouse eggs with mouse sperm. Cryopreservation of mouse sperm. Cryopreservation of rat sperm. Cryopreservation of two-cell and eight-cell mouse and rat embryos.

Molecular biology methods such as DNA purification and PCR reactions. 

Culturing pluripotent mouse embryonic stem cell cultures. 

Maintaining paper records of work activities. Maintaining paper records for regulatory compliance. Maintaining records with computer systems such as MiCores platform, Filemaker databases, shared spreadsheets, calendars, and Microsoft programs. 

Required Qualifications*

• Bachelor’s degree in Biology or similar biomedical field with minimum of four years of relevant experience
• Demonstrated experience in mouse and rat surgical procedures
• Demonstrated experience in molecular biology procedures such as DNA purification and PCR
• Demonstrated experience in mouse embryonic stem cell culture
• Demonstrated experience of highly organized record keeping 
• Highly developed communication skills with people of diverse backgrounds 
• Attention to detail, punctuality, and occasional weekend work required
• Ability to work independently with limited supervision as required
• Excellent interpersonal skills and ability to work with others in a collaborative environment.
• Strong oral and written communication skills
• Proficient in Microsoft office software

Desired Qualifications*

Master's degree in Biology or similar biomedical field

Additional Information

Michigan Medicine values a culture of diversity, equity, and inclusion. Here at the Biomedical Research Core Facilities (BRCF), our dedication to customer service is inseparable from our commitment to diversity, equity and inclusion. It is central to our mission as an institutional resource to ensure that each member of our community has full opportunity to thrive in our environment, for we believe that diversity is key to individual flourishing, educational excellence and the advancement of knowledge.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings.  Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days.  The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

U-M COVID-19 Vaccination Policy

COVID-19 vaccinations are now required for all University of Michigan students, faculty and staff across all three campuses, including Michigan Medicine.  This includes those working or learning remotely.  More information on this policy is available on the Campus Blueprint website or the U-M Dearborn and U-M Flint websites.